Steven E Kahn Selected Research

Metformin (Glucophage)

8/2022	Quantitative trait loci, G×E and G×G for glycemic traits: response to metformin and placebo in the Diabetes Prevention Program (DPP).
12/2021	Prior Glucose-Lowering Medication Use and 30-Day Outcomes Among 64,892 Veterans With Diabetes and COVID-19.
11/2021	Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial.
1/2021	Shape of the OGTT glucose response curve: relationship with β-cell function and differences by sex, race, and BMI in adults with early type 2 diabetes treated with metformin.
1/2021	Association of glycemia with insulin sensitivity and β-cell function in adults with early type 2 diabetes on metformin alone.
1/2021	Association of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort.
1/2021	OGTT Glucose Response Curves, Insulin Sensitivity, and β-Cell Function in RISE: Comparison Between Youth and Adults at Randomization and in Response to Interventions to Preserve β-Cell Function.
4/2019	Erratum. Impact of lifestyle and metformin interventions on the risk of progression to diabetes and regression to normal glucose regulation in overweight or obese people with impaired glucose regulation. Diabetes Care 2017;40:1668-1677.
1/2018	Erratum. Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Diabetes Care 2017;40:1668-1677.
12/2017	Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation.

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Steven E Kahn Research Topics

Disease

94	Insulin Resistance 08/2022 - 04/2002
84	Type 2 Diabetes Mellitus (MODY) 01/2022 - 02/2002
21	Obesity 05/2021 - 04/2002
21	Glucose Intolerance 01/2021 - 07/2002
16	Weight Loss (Weight Reduction) 01/2021 - 12/2006
12	Cardiovascular Diseases (Cardiovascular Disease) 11/2021 - 01/2010
10	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 08/2004
9	Overweight 01/2021 - 06/2014
9	Hypertension (High Blood Pressure) 01/2020 - 10/2003
8	Amyloid Plaque 12/2019 - 02/2003
6	Hyperglycemia 12/2021 - 02/2002
6	Stroke (Strokes) 11/2021 - 04/2010
6	Hypoglycemia (Reactive Hypoglycemia) 01/2020 - 03/2004
5	Myocardial Infarction 11/2021 - 04/2010
5	Prediabetic State (Prediabetes) 01/2021 - 06/2012
5	Heart Failure 11/2020 - 12/2006
5	Non-alcoholic Fatty Liver Disease 11/2019 - 03/2005
4	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2022 - 05/2008
4	Inflammation (Inflammations) 11/2020 - 08/2006
4	Chronic Renal Insufficiency 01/2019 - 02/2013
4	Alzheimer Disease (Alzheimer's Disease) 02/2013 - 11/2005
3	Unstable Angina 11/2021 - 04/2010
3	Body Weight (Weight, Body) 12/2019 - 09/2010
3	Diabetes Mellitus 01/2019 - 07/2015
3	Cognitive Dysfunction 05/2017 - 11/2005
3	Dyslipidemias (Dyslipidemia) 02/2016 - 10/2002
3	Weight Gain 03/2015 - 12/2006
3	Liver Diseases (Liver Disease) 10/2010 - 03/2005
2	COVID-19 12/2021 - 12/2021
2	Proteinuria 09/2021 - 01/2021
2	AIDS-Related Complex (ARC) 01/2021 - 10/2017
2	Heart Diseases (Heart Disease) 11/2020 - 01/2018
2	Abdominal Obesity 01/2020 - 02/2009
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2020 - 02/2013
2	Albuminuria 01/2020 - 01/2018
2	Pancreatitis 09/2019 - 01/2019
2	Kidney Diseases (Kidney Disease) 01/2019 - 01/2016
2	Neoplasms (Cancer) 01/2017 - 03/2004
2	Fatty Liver 10/2010 - 03/2005

Drug/Important Bio-Agent (IBA)

97	Glucose (Dextrose)FDA LinkGeneric 08/2022 - 07/2002
51	Insulin (Novolin)FDA Link 08/2022 - 02/2002
31	Metformin (Glucophage)FDA LinkGeneric 08/2022 - 10/2002
19	Amyloid (Amyloid Fibrils)IBA 11/2020 - 02/2003
16	Islet Amyloid PolypeptideIBA 11/2020 - 02/2002
13	Triglycerides (Triacylglycerol)IBA 01/2021 - 04/2003
11	LipidsIBA 11/2020 - 09/2003
9	C-Reactive ProteinIBA 01/2018 - 10/2002
9	Rosiglitazone (Avandia)FDA Link 05/2011 - 10/2002
8	LinagliptinIBA 09/2021 - 07/2013
8	CholesterolIBA 01/2020 - 08/2003
7	HDL CholesterolIBA 01/2021 - 04/2003
7	Glyburide (Glibenclamide)FDA LinkGeneric 05/2011 - 10/2002
6	C-PeptideIBA 01/2021 - 12/2004
6	LeptinIBA 01/2021 - 04/2002
6	Pharmaceutical PreparationsIBA 01/2021 - 10/2002
6	AdiponectinIBA 01/2021 - 03/2004
5	Peptides (Polypeptides)IBA 01/2022 - 08/2004
5	Proteins (Proteins, Gene)FDA Link 01/2018 - 03/2004
4	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2021 - 12/2006
4	AlbuminsIBA 01/2021 - 10/2002
4	CreatinineIBA 01/2021 - 08/2007
4	HDL LipoproteinsIBA 01/2019 - 12/2010
4	Nonesterified Fatty Acids (NEFA)IBA 01/2019 - 12/2006
4	EnzymesIBA 01/2019 - 10/2007
4	Lipoproteins (Lipoprotein)IBA 06/2011 - 01/2003
4	ThiazolidinedionesIBA 01/2010 - 12/2006
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2010
3	Apolipoproteins E (ApoE)IBA 01/2021 - 05/2017
3	AntigensIBA 01/2021 - 10/2002
3	glimepiride (Amarel)FDA LinkGeneric 09/2019 - 07/2013
3	IsotopesIBA 11/2015 - 02/2009
3	AdipokinesIBA 11/2015 - 03/2013
2	Insulin Glargine (Lantus)FDA Link 11/2021 - 01/2021
2	omega-Chloroacetophenone (Mace)IBA 01/2021 - 01/2020
2	Glucagon (Glukagon)FDA Link 01/2021 - 01/2021
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2020 - 10/2003
2	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 12/2019 - 11/2007
2	LDL CholesterolIBA 01/2019 - 04/2003
2	Hemoglobins (Hemoglobin)IBA 01/2019 - 01/2019
2	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2019 - 01/2008
2	IncretinsIBA 01/2018 - 05/2012
2	Protons (Proton)IBA 11/2015 - 10/2010
2	Antidepressive Agents (Antidepressants)IBA 03/2015 - 06/2014
2	Interleukin-6 (Interleukin 6)IBA 09/2014 - 03/2013
2	CytokinesIBA 09/2014 - 12/2006
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 09/2014 - 07/2013
2	InflammasomesIBA 09/2014 - 10/2010
2	Fatty Acids (Saturated Fatty Acids)IBA 03/2014 - 12/2006
2	IronIBA 03/2014 - 03/2005
2	Transferrin (beta 2 Transferrin)IBA 03/2014 - 03/2005
2	ResistinIBA 07/2013 - 03/2013
2	InterleukinsIBA 07/2013 - 10/2010
2	Neprilysin (Neutral Endopeptidase)IBA 05/2013 - 06/2010
2	Anti-Obesity Agents (Antiobesity Drugs)IBA 06/2011 - 06/2011
2	oxidized low density lipoproteinIBA 09/2010 - 08/2003
2	Nateglinide (Starlix)FDA LinkGeneric 04/2010 - 04/2010

Therapy/Procedure

8	Glycemic Control 03/2015 - 10/2002
4	Bariatric Surgery 03/2014 - 08/2010
4	Therapeutics 06/2011 - 06/2004
2	Gastric Bypass (Roux-en-Y Gastric Bypass) 03/2013 - 08/2010